Discriminative effects of massed extincttion1

Effects of spaced versus massed training in function learning.

A robust finding in the literature is that spacing material leads to better retention than massing; however, the benefit of spacing for concept learning is less clear. When items are massed, it may help the learner to discover the relationship between instances, leading to better abstraction of the underlying concept. Two experiments addressed this question through a typical function learning t...

Discriminative Stimulus Effects in Monkeys

Products containing naphthalen-1-yl-(1-pentylindol-3-yl) methanone (JWH-018) and naphthalen-1-yl-(1-butylindol-3-yl) methanone (JWH-073) are emerging drugs of abuse. Here, the behavioral effects of JWH-018 and JWH-073 were examined in one behavioral assay selective for cannabinoid agonism, rhesus monkeys (n 4) discriminating -tetrahydrocannabinol ( -THC; 0.1 mg/kg i.v.), and another assay sensi...

Associative explanations of discriminative inhibition effects

Discriminative stimulus effects of tramadol in humans.

Tramadol is an unscheduled atypical analgesic that acts as an agonist at μ-opioid receptors and inhibits monoamine reuptake. Tramadol can suppress opioid withdrawal, and chronic administration can produce opioid physical dependence; however, diversion and abuse of tramadol is low. The present study further characterized tramadol in a three-choice discrimination procedure. Nondependent volunteer...

Massed practice versus massed practice with stimulation: effects on upper extremity function and cortical plasticity in individuals with incomplete cervical spinal cord injury.

OBJECTIVE To determine the effect of massed practice (MP) versus massed practice combined with somatosensory stimulation (MP+SS) on cortical plasticity and function in persons with incomplete tetraplegia. METHODS Ten subjects were assigned to either MP or MP+SS. Median nerve stimulation (500 ms train, 10 Hz, 1 ms pulse duration) was delivered at the intensity eliciting a motor threshold respo...